Symbol
Name
ID

Men1
multiple endocrine neoplasia 1
MGI:1316736

Phenotype annotations related to reproductive system

Darker colors indicate more annotations

Human Phenotypes	Ovarian carcinoma	Amenorrhea	Decreased male libido	Impotence
Disease(s) Associated with MEN1	Ovarian carcinoma	Amenorrhea	Decreased male libido	Impotence
multiple endocrine neoplasia type 1
pancreatic cancer

Mouse Phenotypes

decreased uterine NK cell number

abnormal decidualization

increased endometrial gland number

enlarged ovary

increased Leydig cell number

enlarged testis

increased ovary tumor incidence

increased testis tumor incidence

increased Leydig cell tumor incidence

increased gonad tumor incidence

impaired embryo implantation

increased miscarriage rate

reduced female fertility

decreased litter size

Availability

Mouse Genotype

Men1^tm1.1Ctre/Men1⁺

Men1^tm1.1Gfk/Men1⁺

Men1^tm1Rvt/Men1⁺

Men1^tm1Zqw/Men1⁺

Men1^tm2.1Gfk/Men1⁺

Men1^tm1.2Zqw/Men1^tm1.2Zqw
Pgr^tm2(cre)Lyd/Pgr⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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